Threonine

    • Product Name: Threonine
    • Chemical Name (IUPAC): (2S,3R)-2-Amino-3-hydroxybutanoic acid
    • CAS No.: 72-19-5
    • Chemical Formula: C4H9NO3
    • Form/Physical State: Crystalline Powder
    • Factroy Site: Yuanchuang Guojilanwan Creative Park, Huoju Road, Hi-Tech Zone, Qingdao, China
    • Price Inquiry: sales9@boxa-chem.com
    • Manufacturer: Fufeng Biotechnologies Co.,Ltd
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    Specifications

    HS Code

    261963

    Name Threonine
    Iupac Name 2-Amino-3-hydroxybutanoic acid
    Molecular Formula C4H9NO3
    Molar Mass 119.12 g/mol
    Appearance White crystalline solid
    Solubility In Water Soluble
    Melting Point 256°C (decomposes)
    Isoelectric Point 5.65
    Essential Yes (essential amino acid)
    Cas Number 72-19-5
    Chirality Exists as L- and D- isomers (L-form is biologically active)
    Biological Role Proteinogenic amino acid
    Taste Slightly sweet

    As an accredited Threonine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A white, sealed plastic bottle labeled "Threonine, 500g," featuring hazard symbols, batch number, and storage instructions, with a tamper-evident cap.
    Container Loading (20′ FCL) Container Loading (20′ FCL) for threonine: 18-20 metric tons packed in 25kg bags, stacked safely on pallets, moisture-protected.
    Shipping Threonine is shipped in tightly sealed containers, protected from moisture and direct sunlight. It is transported as a non-hazardous, stable amino acid, usually in fiber drums or plastic bags. Standard labeling and documentation are required. Handling should prevent contamination, and appropriate personal protective equipment should be used when managing spills or packaging.
    Storage Threonine should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizers. Avoid exposure to moisture and direct sunlight. Ensure proper labeling and keep the storage area free from combustible materials. Follow standard laboratory practices for chemical storage to prevent contamination and degradation of the compound.
    Shelf Life Threonine typically has a shelf life of 2–3 years when stored in a cool, dry place in tightly sealed containers.
    Application of Threonine

    Purity 98%: Threonine with 98% purity is used in animal feed formulation, where it promotes optimal growth rates and efficient feed conversion.

    Molecular weight 119.12 g/mol: Threonine with molecular weight 119.12 g/mol is used in pharmaceutical synthesis, where it ensures accurate compound formulation and consistency.

    Particle size <100 µm: Threonine with particle size under 100 µm is used in dietary supplement tablet manufacturing, where it provides uniform mixing and tablet hardness.

    Stability at 25°C: Threonine stable at 25°C is used in liquid nutritional products, where it maintains shelf-life and bioavailability.

    Melting point 256°C: Threonine with melting point 256°C is used in heat-processed food systems, where it preserves amino acid structure during processing.

    Assay ≥99%: Threonine with assay ≥99% is used in biotechnological fermentation media, where it maximizes microbial protein synthesis efficiency.

    Moisture content <1%: Threonine with moisture content below 1% is used in powder premixes, where it prevents clumping and ensures product stability.

    Pharmaceutical grade: Threonine of pharmaceutical grade is used in injectable amino acid solutions, where it guarantees sterility and patient safety.

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    Certification & Compliance
    More Introduction

    Threonine: Supporting Animal Health and Production With Reliable Supply

    Looking Past the Basics: The Value of Threonine in Feed Manufacturing

    Walking through our production facilities every day, the commitment to quality always stays front and center—especially with amino acids like threonine. Over the years, we have seen changing trends in feed formulations and customer requests, from pork operations to poultry houses. Threonine remains one of those fundamental products that brings feed manufacturers predictably consistent results, provided it’s sourced pure and handled right.

    Let’s talk openly about the nuts and bolts. Our threonine, model THR98, provides a minimum 98.5% L-threonine on a dry matter basis. The industry often talks about percentages, but what livestock producers care about is the improvement in feed efficiency, growth rates, and animal health—all measured in their barns and by their own eyes. Our technical team often works directly with major feed mills to troubleshoot, reformulate, and review quality control measures, because simply meeting a specification sheet doesn’t say enough about real-world performance.

    Why Amino Acid Profile Matters

    Ration balancing has evolved far past the crude protein era. Now, more facilities optimize for ideal amino acid profiles, keeping environmental and cost concerns in mind. Threonine, after lysine and methionine, is the next limiting amino acid in many swine and poultry diets. That means if a feed falls short in threonine, animals can’t make full use of the protein present—no matter how much soybean meal or synthetic lysine gets added to the ration.

    We have seen firsthand, in both in-house trials and customer-run performance studies, how correcting threonine levels shrinks nitrogen excretion while maintaining or even boosting daily gain. Environmental targets keep getting tighter. These nutrients give nutritionists the flexibility to use lower protein formulas without sacrificing flock or herd performance. As a manufacturing team, we use batch-run analysis data to double-check every lot. Our raw material selection and fermentation process underpin a product that doesn’t swing in threonine content or get bogged down by contaminants.

    Tightening Nutritional Windows and Margin Pressures

    Every feed mill faces cost pressure and ingredient volatility. Threonine becomes a tool for making more competitive rations. Feed formulation software and nutritionist experience come together at the mill, but none of it works if the delivered threonine drifts from its guaranteed assay, carries unwanted byproducts, or varies in particle size.

    Cheaper material may look tempting on a quote sheet, but cutting corners causes headaches just as often as it slashes costs. Bland, powdery off-spec batches clump, feed inconsistently, or throw off mixing times. We keep particle size as close to 40–80 mesh as possible to prevent hang-ups in augers and dosing systems. There’s no substitute for walking the line—sampling, sifting, and checking both bulk cargo and bagged lots, seeing with your own eyes that no clumping or dust cloud is likely to choke the process down the line.

    Supporting the Industry’s Push for Sustainability

    Feed manufacturers and livestock companies face environmental audit pressure, on top of what’s good for business. The data from university and field studies keeps stacking up: adding threonine to low-protein diets means lower manure nitrogen, less odor, and better compliance with local standards.

    As a producer, we value these outcomes, not just for compliance or public image, but because tightening rations and reducing nutrient waste helps every link in the supply chain. Grain counts. By using threonine, it lets nutritionists pull back on expensive proteins yet still hit the targets for weight gain and feed conversion. This brings down the cost per ton of finished feed, with a lower carbon and nitrogen footprint. Large integrators and small regional mills alike can share in these advantages.

    Comparing Threonine to Other Amino Acids

    Plant-sourced proteins bring ups and downs in nutrient consistency; synthetic amino acids fill in the gaps. Lysine and methionine often dominate the talk. But threonine’s spot is unique. Unlike lysine HCl, which can be produced chemically or through fermentation, and methionine, which can be in forms like DL-methionine or methionine hydroxy analogue, our threonine uses a tried-and-tested liquid fermentation model that gives better purity, batch-to-batch reliability, and less risk of off-flavors in the feed.

    Some imports compete on price, but past analysis has shown us ranges from 90% active up to 98%, with glaring differences in dustiness, particle size, and levels of residual carrier or unwanted byproducts. A lot of our long-term clients have moved to premium threonine after seeing poor flowability or delivery headaches with inferior goods. In pelleted and extruded feeds, our on-site milling partners see far less risk of grinder blockages or uneven distribution when working with a free-flowing, fine but not fluffy powder.

    The story with threonine vs. methionine is also about metabolism. Poultry will respond rapidly to threonine adjustments in terms of gut health and feathering, where methionine is more tied to growth. Our threonine line has helped balance broiler and layer diets by matching what birds actually require—no more, no less. In piglets, threonine tightens up gut integrity, something our field partners appreciate during challenging post-weaning transitions.

    Specifications That Deliver in Practice

    Some clients ask about heavy metals, solvent residues, and microbial safety. We keep lead, cadmium, arsenic, and mercury below the toughest industry thresholds. Salmonella and coliforms get screened on every production batch using our lab’s rapid-test protocols—right at the plant, not shipped elsewhere.

    Moisture holds steady below 1%, which means better shelf life, improved mixing accuracy, and no caking during transport. The pH stays just above neutral, reducing risk of feed instability and limiting corrosiveness to premix systems. Real-world testing gives us the confidence to back our specifications with guarantees written into every supply agreement.

    Handling, Mixing, and Compatibility

    Threonine feeds easily using both micro-dosing and manual weighing systems. Its pale color and low odor profile remove any fear of feed off-note or rejection at the trough. We don’t include flow aids, binders, or anti-caking agents that compromise purity, so formulation and mixing teams can fine-tune without surprise interactions.

    In multi-stage mixing systems, our threonine keeps particle size distribution consistent. Bagged or bulk product moves through pneumatic, screw, and vibratory feeders with just minor tweaks to auger speed. We support facilities with advice on tank cleaning and dilution protocols, ensuring no residues or bridging occurs between batches. Our technical team runs on-site troubleshooting for plants moving from low-protein to optimized amino acid formulas, supporting the entire transition.

    Consistent Quality Through Every Batch

    Feed manufacturers rely on routine, not surprises. We start at the fermentation level: keeping yeast and bacteria strains pure, monitoring nutrient feeds, and running HPLC checks throughout the growth curve. After each run, we pull samples from every production line—silo, tote, and finished packaging. Messaging flows rapidly between the lab team, line managers, and quality assurance before releasing for shipment.

    Our facilities have weathered surges in energy costs, supply interruptions on key ingredients, and stricter local emissions controls. Automation and process control are key, but it’s hands-on experience—walking the line, checking with nose, eye, and touch—that keeps surprises out of finished lots. We stick with our rigor because it shows in the feedback from our mill partners: no off-color, reliable mix, and feed results that match the formulation model.

    Supporting Partners With Data and Experience

    Clients from across livestock sectors contact us to get guidance on switching to threonine or tweaking their formulas. They want facts, not empty sales talk. Our team shares feed trial data, helps analyze blood urea levels and nitrogen excretion rates, and runs digestibility assays on threonine under both commercial and controlled conditions.

    In some cases, nutritionists press for lower total dietary protein to manage costs or environmental outputs, then trust us to show the impact of these changes in high-density finisher or starter rations. We run comparison trials side-by-side with soybean meal-only and synthetic-amino-acid rations, so everyone sees the full economic and performance impact. Integration and collaboration give us insights into what works—so our advice grows from grounded results, not just best-guess predictions.

    No Corners Cut, No Surprises in Supply

    We run continuous investment in our production lines for both food safety and feed safety. Microbes, air quality, and water are monitored daily. We own every batch of threonine produced—no white label, no mystery blend, no cutting with carriers or flow agents from unknown sources.

    This direct approach lets us respond rapidly to custom orders, whether that means changing bagging, varying mesh size, or developing new technical documentation for specific geographic requirements. Our track record with large integrators and boutique feed mills alike shows one thing: reliability, both in what we deliver and how we communicate.

    Global Supply, Local Trust

    Being a primary manufacturer gives us the power to set both product standards and delivery schedules. During COVID disruptions, partners at major export hubs saw delays and price crashes from lower-tier resellers. Our warehouse and direct logistics teams prioritized safe handling, clear border paperwork, and real-time alerts to downstream clients.

    Why does this matter? Because consistency means everything during a crisis. Plants can’t afford inconsistent deliveries or poor-performing lots. We keep extra capacity at our main sites, so rush orders or seasonality won’t mean late shipments or diluted product. This management style has built trust that lasts through unpredictable years.

    Working With Feed Formulators and Nutritionists

    We don’t sell and walk away. Our role is to be a partner, not just a supplier. Feed nutrition is always changing—protein prices swing, new animal health challenges emerge, and environmental regulators keep raising the bar. By staying close with nutritionists and feed formulation teams, we get a front-row seat to the shifting needs in the field.

    For example, off-odor batches or visible dust have led some plants to rethink previous purchasing decisions. Our team makes site visits, collects samples, and reviews handling protocols in real-world conditions. When expansion plans mean higher linespeeds or new ingredient additions, we communicate directly about risk, feed interaction, and pellet quality—well before challenges show up on the finished feed.

    Commitment to Transparency

    We publish assay data batches side-by-side with every shipment, not just on request. Clients can trace every order’s history back to production day, ingredient inputs, plant location, and complete QC records. If a specification line needs an update due to changes in feed law, we work quickly with customers to revalidate and document, so nobody plays catch-up after an audit.

    Why Choosing the Right Threonine Source Pays Off

    Getting the right product matters, and many years in this business reinforce this point. A lower upfront price may look great, but once fines, mixing headaches, and animal performance drag start to add up, the “savings” shrink. Our focus stays on delivering reliable, well-documented threonine that gives tangible value to clients, not just in feeding trials but at the end of the financial year.

    The Future of Threonine: Flexible, Responsive, and Always Accountable

    Our product line will keep growing, and new dietary strategies will push us to keep improving. Feed manufacturers want more detailed amino acid digestibility data, faster turnaround on custom batch requests, and suppliers who can troubleshoot alongside them on plant floors and in mixing rooms.

    We take these challenges seriously because we live them daily. Being a manufacturer means feeling responsible for every pallet, every sack, every feed bin that our threonine fills. Success, for us, is measured not only in tons moved but in the feedback from nutritionists and plant managers who see fewer complaints, stronger animal growth, and lower feed costs.

    Steadfast Performance in a Changing Industry

    Looking ahead, sustainability goals, animal welfare, and resource management will stay core concerns. Synthetic threonine, produced with traceable, audit-friendly methods like ours, brings livestock operations closer to these targets. The changes may not happen in one season. But each ton of threonine that helps reduce nitrogen waste, improves animal health or lowers ration costs is a step in the right direction.

    As markets shift and requirements grow tighter, we remain committed to delivering threonine that stands out in quality, safety, and partner support. It’s a responsibility we welcome, every day, batch after batch.